EN FACE VERSUS 12-LINE RADIAL OPTICAL COHERENCE TOMOGRAPHY SCAN PATTERNS FOR DETECTION OF MACULAR FLUID IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION
| Autor: | Joseph I. Maguire, Jason Hsu, Allen C. Ho, Abtin Shahlaee, Murtaza K. Adam, Wasim A. Samara |
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| Rok vydání: | 2020 |
| Předmět: |
genetic structures
medicine.diagnostic_test business.industry Spectral domain General Medicine Gold standard (test) Macular degeneration medicine.disease eye diseases 03 medical and health sciences Ophthalmology 0302 clinical medicine Clinical decision making Optical coherence tomography Age related 030221 ophthalmology & optometry medicine sense organs 030212 general & internal medicine Tomography Nuclear medicine business Raster scan |
| Zdroj: | RETINAL Cases & Brief Reports. 14:53-60 |
| ISSN: | 1935-1089 |
| DOI: | 10.1097/icb.0000000000000616 |
| Popis: | Purpose To compare fluid detection of autosegmented en face to 12-line radial spectral domain optical coherence tomography scan patterns in neovascular age-related macular degeneration. Methods Retrospective observational case series. Sixty-seven patients (94 eyes) with neovascular age-related macular degeneration underwent autosegmented en face optical coherence tomography (with associated 304-line raster scan) and 12-line radial scan patterns. Sensitivity and specificity of fluid detection for en face scan and 12-line radial scans were determined by combining radial and 304-line raster scans as a gold standard. Results Two hundred and fifty-eight en face and 12-line radial spectral domain optical coherence tomography scans were interpreted. Seventy-five scans (58.1%) had fluid, whereas 54 scans (41.9%) did not. En face scan pattern fluid detection sensitivity and specificity was 89.3% and 61.1%, respectively. Twelve-line radial scan pattern fluid detection sensitivity and specificity was 97.3% and 100%, respectively. The difference in fluid detection between scan patterns was statistically significant (P = 0.01). Decreased central macular thickness was associated with false-positive (P = 0.035) and false-negative (P = 0.01) fluid detection on en face scans. Conclusion En face optical coherence tomography alone is not as sensitive or specific as the 12-line radial scan pattern in detecting fluid in neovascular age-related macular degeneration. En face scans should be corroborated with other optical coherence tomography protocols to guide clinical decision making. |
| Databáze: | OpenAIRE |
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