ChemInform Abstract: Preparation and Evaluation of a Cyclic Acyl Nitrone as a Synthon for Stereospecific α-Amino Acid Synthesis

Autor:	Andrew T. McPhail, Steven W. Baldwin, Bruce G. Young
Rok vydání:	2010
Předmět:	chemistry.chemical_classification Stereospecificity chemistry Stereochemistry Synthon Organic chemistry General Medicine Optically active Amino acid synthesis Nitrone
Zdroj:	ChemInform. 29
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199849204
Popis:	The preparation and characterization of cyclic optically active (5R)-3,4,5,6-tetrahydro-5-phenyl-2H-1,4-oxazin-2-one-N-oxide (2) is described. This nitrone, which is viewed as a template for the synthesis of γ-oxygenated α-amino acids, reacts with alkenes efficiently and with high stereospecificity.
Databáze:	OpenAIRE
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