Analysis of 154 T4 Colorectal Cancer Patients with Peritoneal Carcinomatosis Treated by Surgery

Autor:	Jing-Lin Liang, Meijin Huang, Wei Chen, Yan Zhang, Jun-Wen Ye, Xiao-ping Tan
Rok vydání:	2021
Předmět:	Univariate analysis medicine.medical_specialty Multivariate analysis Colorectal cancer business.industry medicine.disease Palliative surgery Surgery Metastasis Peritoneal carcinomatosis medicine Overall survival Good prognosis business
Zdroj:	International Journal of Clinical Medicine. 12:61-70
ISSN:	2158-2882 2158-284X
Popis:	Objective: The purpose of this study was to observe the factors related to T4 patients who underwent surgery for colorectal cancer (CRC) with peritoneal carcinomatosis. Methods: 154 T4 colorectal cancer patients who underwent surgery in the first Affiliated Hospital of Sun Yat-sen University were included in the study between August, 1994 and December, 2005. Some clinical variables were selected and statistically correlated with prognosis. Results: The overall survival time was 91.7 months at the end of December of 2010 or death. The complete cytoreduction had significant survival benefit than the palliative surgery group. The age, location, histological grade, complete cytoreduction and liver metastasis were associated with overall survival time (OS) according to the univariate analysis (P < 0.05). In addition, Cox multivariate analysis showed that the complete cytoreduction (CCR) and liver metastasis were independent factor influencing survival. Conclusion: Compared with palliative surgery, the incomplete cytoreduction fails to improve patient prognosis. Patients performed completed cytoreduction have a relative good prognosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::85a2570e7e5b2f7693f168fadda73d2f https://doi.org/10.4236/ijcm.2021.122008 Zobrazit plný text záznamu