ChemInform Abstract: Thiazole-Diamides as Potent γ-Secretase Inhibitors

Autor:	Chandra B. Gamlath, Barbara G. Sahagan, Kevin Cherry, Christine E. Oborski, Dane R. Liston, Charles F. Ebbinghaus, Barbara-Anne Martin, Michael L. Corman, Yuhpyng L. Chen
Rok vydání:	2008
Předmět:	chemistry.chemical_compound chemistry Stereochemistry Ic50 values macromolecular substances General Medicine γ secretase Thiazole
Zdroj:	ChemInform. 39
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200804223
Popis:	The thiazole-diamide series (1) has been identified as highly potent γ-secretase inhibitors. Several representative compounds showed IC50 values of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::857f1fe596b56b1f09b2641bcfccebfc https://doi.org/10.1002/chin.200804223 Zobrazit plný text záznamu Plný text