Development, reliability and validation of a neurogenic bowel dysfunction score in pediatric patients with spina bifida

Autor: Antoine E. Khoury, Brenda Cassidy, Guy Hidas, Maryellen S. Kelly, Margaret Hannan, Gordon McLorie, Blake Selby
Rok vydání: 2014
Předmět:
Zdroj: Neurourology and Urodynamics. 35:212-217
ISSN: 0733-2467
DOI: 10.1002/nau.22694
Popis: Objective To develop a reliable and valid questionnaire to monitor neurogenic bowel symptoms in children. Patients Thirty-four children aged 6–18 with neurogenic bowel and their caregivers. Eighteen control patients. Methods An expert panel generated a domain of observables and formative/reflective content. Response options were scaled following Likert-type items. Key informant interviews revised the measures. A final questionnaire was given to patients twice to calculate intra-rater reliability using Cohen's Kappa Coefficient (k) and paired t-test. Blinded interviews were conducted after physical examination and health assessment and questionnaires completed by a nurse to determine construct validity and inter-rater reliability using k and Spearman's rank-order correlation. Control patients completed the questionnaire once, their results were used to determine discriminate validity and a receiver operating characteristic (ROC) curve. Results Intra-rater reliability showed 85% of the questionnaires having k >0.6. Paired t-test results of t(33) = 1.997, P = 0.054, d = 0.53, confirmed there was not a significant difference between the scores of the two completed questionnaires. Inter-rater reliability showed 97% of the questionnaires having k >0.6 between the nurse and the patient/caregiver responses. Scores had a strong positive correlation at rs(32) = 0.943, P
Databáze: OpenAIRE
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