A fetus coexisting with a complete hydatidiform mole with trisomy 9 of maternal origin
| Autor: | Kam Cheong Lee, Mark D. Pertile, Wing Cheuk Wong, Mary Hoi Yin Tang, Chun Hong So, Anita Sik Yau Kan, Wan Pang Chan, Elizabeth T. Lau |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Fetus Complete hydatidiform mole medicine.medical_specialty Pathology business.industry Cytogenetics Obstetrics and Gynecology Molecular genotyping medicine.disease Trisomy 9 Diploidization Multiple Gestation 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis medicine Placental pathology business reproductive and urinary physiology |
| Zdroj: | Journal of Obstetrics and Gynaecology Research. 44:955-959 |
| ISSN: | 1341-8076 |
| DOI: | 10.1111/jog.13598 |
| Popis: | A complete hydatidiform mole (CHM) coexisting with a viable fetus is a rare finding in pregnancies. Accurate diagnosis often relies on ultrasonographic, histopathological and molecular techniques in the definite diagnosis. To the best of our knowledge, a liveborn fetus coexisting with CHM with trisomy 9 has not been described. The use of molecular genotyping and immunohistochemical laboratory investigations enabled the CHM to be fully characterized. Postzygotic diploidization of a triploid conception arising from dispermy is the proposed mechanism of its formation. |
| Databáze: | OpenAIRE |
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