TREATMENT OF TWO-FACTOR PATHOLOGY CAUSED BY THERMAL INJECTION ON THE BACKGROUND OF EXTERNAL GAMMA – RADIATION

Autor: Fsbsi, Ru.N. Nizamov, biological safety, Timur R. Gaynutdinov, Konstantin N. Vagin, A.M. Idrisov, Ra.N. Nizamov, N.M. Vasilevsky
Rok vydání: 2021
Předmět:
Zdroj: Scientific Notes Kazan Bauman State Academy of Veterinary Medicine. 245:17-24
ISSN: 2413-4201
DOI: 10.31588/2413-4201-1883-245-1-17-24
Popis: A two-factor lesion of radiation and burn diseases separately and their combination was modeled. It was found that external γ-irradiation of white rats at a dose of 7.5 Gy causes severe ra-diation sickness with a high mortality rate. At the same time, it was noted that the degree of thermal burn depends on the time of contact with the body surface of a metal plate heated to 190 ° C: its application for 5 seconds causes a III A degree burn, an 8 second exposure - III B degree, as evi-denced by the timing of formation, rejection burn scab and complete healing of thermal injuries. The aggravating effect of ionizing radiation on the course and outcome of combined radiation-thermal pathology was shown. For the treatment of the studied pathology, the drug "OSK" was used, which was applied subcutaneously directly under the burned area of the skin in a dose of 0.4 ml after radi-ation and thermal effects on the body.
Databáze: OpenAIRE