Unique, one-step, double isomerization (2E,4Z .dblharw. 2Z,4E) of 6-oxo-2,4-heptadienoic acid catalyzed by maleylacetone cis-trans isomerase

Autor:	Stanley Seltzer, Anthony L. Feliu, Karl J. Smith
Rok vydání:	1984
Předmět:	chemistry.chemical_classification Chemistry Stereochemistry One-Step General Chemistry Isomerase Biochemistry Maleylacetone Chemical reaction Catalysis NMR spectra database Colloid and Surface Chemistry Enzyme Isomerization Cis–trans isomerism
Zdroj:	Journal of the American Chemical Society. 106:3046-3047
ISSN:	1520-5126 0002-7863
DOI:	10.1021/ja00322a057
Popis:	In order to examine the structural requirements of the enzyme, maleylacetone cis-trans isomerase, the enzyme, 6-oxo-2,4-heptadienoic acids, and its methyl esters were synthesized to provide the four possible cis-trans isomeric skeletons. The compounds are reported. The reported results suggest that the enzyme binds maleylacetone in the region of the 6-oxo function as well as by its carboxyl group. 6 references, 1 figure.
Databáze:	OpenAIRE
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