A new structural analogue antagonist of peptido-leukotrienes. The discovery of bay x7195
| Autor: | H.C. Kluender, W. Hartwig, P. J. Gardiner, Peter Norman, Trevor S. Abram, Francis Hilary P, H. Böshagen, J.E. Butler, Heinrich Meier, Tudhope Stephen, Nigel J. Cuthbert, K.H. Schlemmer, William A. Taylor, Ulrich Rosentreter |
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| Rok vydání: | 1993 |
| Předmět: |
Leukotriene D4
Chemistry Stereochemistry Organic Chemistry Clinical Biochemistry Antagonist Pharmaceutical Science Chemical modification Biological activity respiratory system Biochemistry chemistry.chemical_compound Drug Discovery Molecular Medicine lipids (amino acids peptides and proteins) Molecular Biology Bay |
| Zdroj: | Bioorganic & Medicinal Chemistry Letters. 3:1517-1522 |
| ISSN: | 0960-894X |
| DOI: | 10.1016/s0960-894x(00)80009-8 |
| Popis: | Systematic modification of LTD4 has led to the discovery of BAY x7195, a potent, selective, orally-active peptido-leukotriene antagonist. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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