Asymmetric Syntheses of Both Enantiomers of Amphetamine Hydrochloride via Bakers’ Yeast Reduction of Phenylacetone

Autor:	Li Kang, Fei Yi, Xiao-Xin Shi, Chun-Li Shen, Jian-Zhong Yao
Rok vydání:	2004
Předmět:	010405 organic chemistry Chemistry Stereochemistry Phenylacetone Enantioselective synthesis General Chemistry 010402 general chemistry Bakers Yeast 01 natural sciences Yeast 0104 chemical sciences chemistry.chemical_compound Amphetamine Hydrochloride Enantiomer
Zdroj:	Journal of Chemical Research. 2004:681-683
ISSN:	2047-6507 1747-5198
DOI:	10.3184/0308234043431843
Popis:	Both enantiomers of amphetamine hydrochloride were stereospecifically synthesised based on bakers’ yeast reduction of phenylacetone. A simple and efficient method for the chiral inversion of (S)-1-phenyl-2-propanol 3 to (R)-1-phenyl-2-propanol 8 has been discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8529a2a8cf7793ca7b5244d77a29e420 https://doi.org/10.3184/0308234043431843 Zobrazit plný text záznamu