Comparison of high-intensity interval training and moderate-intensity continuous training in their effects on behavioral functions and CORT levels in streptozotocin-induced diabetic mice
| Autor: | Namdar Yousofvand, Sana Sabaghi, Fateme Sadeghi, Ali Heirani, Ayoob Sabaghi |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Sports medicine business.industry 030229 sport sciences 030204 cardiovascular system & hematology Streptozotocin medicine.disease Interval training Motor coordination 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology chemistry Corticosterone Internal medicine Diabetes mellitus medicine Orthopedics and Sports Medicine Effects of sleep deprivation on cognitive performance business High-intensity interval training medicine.drug |
| Zdroj: | Sport Sciences for Health. 17:119-126 |
| ISSN: | 1825-1234 1824-7490 |
| DOI: | 10.1007/s11332-020-00661-3 |
| Popis: | Neurodegenerative disorders, such as deficits in cognition and motor coordination, are associated with diabetes mellitus (DM). It is believed that Corticosterone (CORT) has a role in behavioral functions. Exercise is beneficial on neurobehavioral impairment in DM; however, the debate about the value of high-intensity interval training (HIIT) vs. moderate-intensity continuous training (MICT) has been long-lasting. In the present study, we evaluated the effects of HIIT and MICT on cognitive performance, motor coordination, and serum CORT level using streptozotocin (STZ)–induced diabetes mice. We used STZ (50 mg/kg, i.p.) for five consecutive days to induce diabetes, followed by treatment with MICT and HIIT for 8 weeks. STZ-induced chronic diabetes significantly induced cognitive deficiency and motor coordination impairment in mice (p |
| Databáze: | OpenAIRE |
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