Abnormal liver enyzmes in outpatients with eating disorders
| Autor: | Felice R. Zwas, Phyllis Roloff, David Greenfeld, Diane Mickley, Donald M. Quinlan |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
education.field_of_study biology business.industry Population Aspartate transaminase Anorexia medicine.disease Anorexia nervosa Gastroenterology Transaminase Psychiatry and Mental health Eating disorders Endocrinology Alanine transaminase Internal medicine medicine biology.protein medicine.symptom business education Body mass index |
| Zdroj: | International Journal of Eating Disorders. 20:325-329 |
| ISSN: | 1098-108X 0276-3478 |
| Popis: | Objective This study was undertaken to screen a large series of outpatients with anorexia or bulimia for liver enzyme abnormalities, examining their frequency and their clinical correlates. Method: Eight hundred seventy-nine eating-disordered outpatients presenting at a suburban clinic constituted the subject population. Serum glutamic oxalacetic transaminase, serum glutamic pyruvate transaminase, and gamma glutamyl transpeptidase (SGOT, SGPT, and GGTP, respectively) were drawn at intake. Medical charts were reviewed to obtain further clinical data on all patients with an enzyme elevation. Results: Liver enzymes were abnormally high in 36 patients (4.1%). Elevated SGPT was the most frequent enzyme abnormality and was correlated with lower current and past weight and body mass index (BMI). Discussion: Hepatic dysfunction in eating-disordered outpatients is neither specific nor common. Low weight alone can cause liver damage, yet elevated liver chemistries in patients with anorexia and especially bulima are often not due to their eating disorder. © 1996 by John Wiley & Sons, Inc. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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