High Throughput Screening
| Autor: | M.S. Attene-Ramos, Menghang Xia, C.P. Austin |
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| Rok vydání: | 2014 |
| Předmět: | |
| DOI: | 10.1016/b978-0-12-386454-3.00209-8 |
| Popis: | High throughput screening (HTS) is capable of screening large compound libraries for activity with a diverse portfolio of biologically relevant endpoints. In comparison to traditional single-concentration HTS, titration-based quantitative high throughput screening (qHTS) is especially useful in toxicology because of its capacity to profile thousands of chemicals in concentration-response format, with greatly reduced rates of false positives and false negatives. |
| Databáze: | OpenAIRE |
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