Monoclonal Antibody Therapy: 'Model' Experiments with Toxin-Conjugated Antibodies in Mice and Rats

Autor:	S. I. Detre, Walter C. J. Ross, Don Mason, Philip E. Thorpe, A. J. Cumber
Rok vydání:	1983
Předmět:	Cell fusion biology medicine.drug_class Chemistry Immunoglobulin Fab Fragments medicine.medical_treatment Immunotherapy Monoclonal antibody Cell culture Cancer cell biology.protein medicine Cancer research Antibody Monoclonal antibody therapy
Zdroj:	Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ISBN: 9783540118589
DOI:	10.1007/978-3-642-68761-7_24
Popis:	The advent of cell fusion techniques for producing monoclonal antibodies has stimulated world-wide effort in the search for antibodies with specificity for neoplastic cells. In parallel, a number of laboratories have attempted to devise ways of attaching cytotoxic agents to antibodies with the aim of generating potent anticancer agents from monoclonal antibodies that exhibit sufficient specificity for cancer cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::84fec76a38efc805dd5bb0dce0916be5 https://doi.org/10.1007/978-3-642-68761-7_24 Zobrazit plný text záznamu