| Autor: |
Howard Eichenbaum, R. Jonathan Robitsek, Christopher J. MacDonald, Benjamin J. Kraus, Robert W. Komorowski |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
The Neurobiological Basis of Memory ISBN: 9783319157580 |
| Popis: |
Ray Kesner long ago proposed that the hippocampus supports the organization of memories by their spatial and temporal attributes, and he generated compelling evidence for this proposal through many creative experimental analyses of the effects on memory resulting from damage to the hippocampus. Here I describe some of that evidence and other studies of the firing properties of hippocampal neurons that offer insight into the mechanisms of spatial and temporal organization that underlie hippocampal dependent memory. Hippocampal neurons parse the layout of spatial contexts by “place cells” that represent memories in the locations where they occur, and they parse the temporal organization of experiences by “time cells” that represent the moments when memories occur. The combination of mapping place and time constitutes a mechanism for organizing spatial–temporal context as a fundamental attribute of the memory capacity supported by the hippocampus. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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