Ion Exchange Method for Determining Mephentermine Sulfate in Drug Formulations: Collaborative Study
Autor: | Rod Chu, Elaine J Friedman |
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Rok vydání: | 1978 |
Předmět: | |
Zdroj: | Journal of AOAC INTERNATIONAL. 61:60-64 |
ISSN: | 0004-5756 |
DOI: | 10.1093/jaoac/61.1.60 |
Popis: | Ion exchange chromatography is used to separate mephentermine sulfate from drug formulations. The drug is subsequently measured by ultraviolet spectrophotometry. Assays on 4 commercial samples of tablets and injectables gave recoveries from 97.6 to 104% of declared. A collaborative study involving 2 tablet and 2 liquid formulations gave mean recoveries ranging from 94.7 to 99.3% and coefficients of variation from 1.39 to 2.00%. |
Databáze: | OpenAIRE |
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