Ion Exchange Method for Determining Mephentermine Sulfate in Drug Formulations: Collaborative Study

Autor: Rod Chu, Elaine J Friedman
Rok vydání: 1978
Předmět:
Zdroj: Journal of AOAC INTERNATIONAL. 61:60-64
ISSN: 0004-5756
DOI: 10.1093/jaoac/61.1.60
Popis: Ion exchange chromatography is used to separate mephentermine sulfate from drug formulations. The drug is subsequently measured by ultraviolet spectrophotometry. Assays on 4 commercial samples of tablets and injectables gave recoveries from 97.6 to 104% of declared. A collaborative study involving 2 tablet and 2 liquid formulations gave mean recoveries ranging from 94.7 to 99.3% and coefficients of variation from 1.39 to 2.00%.
Databáze: OpenAIRE