Determination of oxidative stress markers and serum cholinesterase among pesticide sprayers in southern Brazil

Autor:	Bernardo Erdtmann, J. da Silva, João Antonio Pêgas Henriques, Diana Lilian Bordin, Mirian Salvador, Ana Cristina Andreazza
Rok vydání:	2008
Předmět:	biology Thiobarbituric acid Health Toxicology and Mutagenesis Pesticide medicine.disease_cause Pollution Toxicology Superoxide dismutase chemistry.chemical_compound chemistry Catalase Toxicity medicine biology.protein TBARS Environmental Chemistry Oxidative stress Cholinesterase
Zdroj:	Toxicological & Environmental Chemistry. 90:809-814
ISSN:	1029-0486 0277-2248
Popis:	Small farmers generally spray pesticides manually and often do not use complete protective equipment. The standard test to detect pesticide exposure, which may be associated with toxicity, is the determination of serum cholinesterase, but in chronic exposure to low doses, this test is less sensitive. In this study, in a group sampled among pesticide sprayers without signs of intoxication, cholinesterase, thiobarbituric acid reactive substances (TBARS), catalase (Cat), and superoxide dismutase (Sod) activities were analyzed. Cholinesterase activity was only slightly lower in the farmer group in relation to the control group. However, TBARS and Cat activities were 3-fold increased in the farmers in comparison to the controls. Sod activity was similar in both groups. The group of pesticide sprayers that did not use the complete protective equipment presented a significantly higher level of TBARS than the group that used the complete protective equipment. Therefore, the determination of TBARS and catalase can...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::84b6450bbd02728260c160574848c5a8 https://doi.org/10.1080/02772240701742656 Zobrazit plný text záznamu