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INTRODUCTION: Cardiovascular diseases are the main cause of death in patients with type 1 diabetes mellitus (T1DM) and atherosclerotic process begins in childhood. OBJECTIVE: To evaluate lipid profile of patients with T1DM accompanied at the pediatric endocrinology (UEP), Hospital de Clínicas, Federal University of Paraná (HC-UFPR), the prevalence of dyslipidemia and its correlation with glycemic control, duration of T1DM, family history of dyslipidemia and nutritional profile status. METHODS: Data of diagnostic information, comorbidities, birth weight, sex, family history of diabetes, dyslipidemia and heart diseases were reviewed. Anthropometric measurements, glycemic control, blood pressure (BP), lipid profile, and pharmacological treatment for dyslipidemia were obtained in four moments: after three months of diagnosis (t1), two (t2), five (t3), and ten (t4) years of illness. RESULTS: 228 patients (122 girls), mean age at diagnosis of 7.3 years, were included. In t3 and t4 there was a significant increase in BP elevation. Prevalence of dyslipidemia was 31.7% in t1, 33.7% in t2; 37.4% in t3; and in 63.6% in t4. There was a significant increase in total cholesterol and LDL-cholesterol level over time (p |
