Safe discharge of patients with low-risk upper gastrointestinal bleeding (UGIB): Can the use of Glasgow-Blatchford Bleeding Score be extended?
| Autor: | Indra Neil Guha, D Farrugia, Manwani R, Adam L. Gordon, Martin W. James, Le Jeune Ir |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Blood transfusion medicine.diagnostic_test business.industry medicine.medical_treatment Vital signs Interventional radiology Retrospective cohort study General Medicine Emergency department Critical Care and Intensive Care Medicine medicine.disease Internal medicine Severity of illness Emergency Medicine Internal Medicine medicine Upper gastrointestinal bleeding business Rockall score |
| Zdroj: | Acute Medicine Journal. 10 |
| ISSN: | 1747-4884 |
| DOI: | 10.52964/amja.0506 |
| Popis: | Introduction: Risk stratification of patients with suspected upper gastrointestinal bleeding (UGIB) using either Glasgow-Blatchford Bleeding Score (GBS) or preendoscopy Rockall score to facilitate early safe discharge (GBS=0, pre-Rockall=0) has been reported. This observational study compared score utility and considered the impact of extending the range of GBS or pre-Rockall scores permitting safe discharge. Methods: Consecutive adult patients presenting to acute medical admissions or the emergency department from September 2008-March 2009 with suspected UGIB had clinical history, vital signs, laboratory and endoscopy results prospectively recorded using electronic databases. GBS, pre-Rockall scores and a composite endpoint (blood transfusion, endoscopic therapy, interventional radiology, surgery or 30-day mortality) were calculated. Results: 388 patients with suspected UGIB were identified of which 92.3% were admitted (median (range) GBS=5 (0-19) and pre-Rockall=2 (0-11)) and 7.7% discharged (GBS=0 (0-4) and pre-Rockall=0 (0-4)). 186 (47.9%) underwent in-patient endoscopy. 151 (38.9%) were found to have the composite endpoint with 77.5% having transfusion, 45.7% endoscopic treatment and an 8.0% mortality within 30 days. AUROC (95% CI) for 30-day composite endpoint was 0.92 (0.89-0.94) using GBS and 0.75 (0.70-0.80) using pre-Rockall scores. Analysis using different GBS thresholds demonstrated that GBS=0, GBS ≤1 and GBS≤2 had superior utility in identifying freedom from an adverse clinical outcome at 30-days than pre-Rockall score 0. Conclusions: GBS is superior to pre-Rockall score in identifying patients with suspected UGIB who have a low likelihood of an adverse clinical outcome and can be considered for early discharge. Diagnostic performance at different thresholds suggests that patients with GBS≤2 could be considered for early discharge, doubling the number of eligible patients (15.2 to 32.5%). This has important patient safety and resource implications. |
| Databáze: | OpenAIRE |
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