Comparison of Agatston CT coronary artery calcium score, Framingham score and blood biomarkers as predictors of coronary artery stenosis

Autor:	Vesna Pehar-Pejčinović, Vedran Bursic, Zeljko Madzar, Viktor Peršić, Dragan Javoran, Ana Lanca, Marko Boban
Rok vydání:	2013
Předmět:	medicine.medical_specialty Framingham Risk Score business.industry Atrial fibrillation Context (language use) medicine.disease Coronary artery disease Stenosis Internal medicine Relative risk medicine Cardiology Cardiology and Cardiovascular Medicine business Agatston score Coronary atherosclerosis
Zdroj:	Cardiologia Croatica. 8:e7-e8
ISSN:	1848-5448 1848-543X
Popis:	Purpose: Coronary CT angiography (CCTA) with calcium scoring measured with Agatston score index provides a diagnosis of coronary atherosclerosis in patients with subclinical coronary plaque. We compared diagnostic accuracy of Agatston score, Framingham Risk score and multiple blood biomarkers in predicting coronary artery disease (CAD) that caused stenosis >50%. Methods: This retrospective single-center study is evaluating the role of Agatstone score in prognostication of coronary artery stenosis in patients who presented with atypical chest pain and non conclusive stress test result. The study included 368 patients with unknown coronary heart disease (mean age 62.2±7.7; 62% of females) who underwent CCTA and obtained Agatston score, in our Center from June 2012 till June 2013. Scanning was done with dual-source MDCT (Somatom Definition FLASH; Siemens Medical Solution, Munich, Germany) equipped with two 128-detector row units using the prospective or retrospective ECG-gating protocol and the mean received amount radiation was 6.85±9.74mSv. Exclusion criteria included pre-existing kidney failure (eGFR
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::84569b1882ea12bce1952d4e78f885c6 https://doi.org/10.15836/ccar.2013.e7 Zobrazit plný text záznamu Plný text ve formátu PDF