A turn-on fluorescent lysine nanoprobe based on the use of the Alizarin Red aluminum(III) complex conjugated to graphene oxide, and its application to cellular imaging of lysine
| Autor: | Huiying Huang, Liming Dai, Congcong Ge, Rumei Cheng, Shengju Ou, Yu Peng, Bu Yexu, Yuhua Xue, Hongyan Liu |
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| Rok vydání: | 2017 |
| Předmět: |
Graphene
Chemistry Lysine Inorganic chemistry Nanoprobe ALIZARIN RED 02 engineering and technology Conjugated system 010402 general chemistry 021001 nanoscience & nanotechnology Photochemistry complex mixtures 01 natural sciences Fluorescence Photoinduced electron transfer 0104 chemical sciences Analytical Chemistry law.invention law bacteria 0210 nano-technology Ternary complex |
| Zdroj: | Microchimica Acta. 184:3521-3528 |
| ISSN: | 1436-5073 0026-3672 |
| DOI: | 10.1007/s00604-017-2375-0 |
| Popis: | The authors describe a rationally designed nanoprobe for the fluorometric determination of lysine. It is based on a ternary complex consisting of graphene oxide, aluminum ions (acting as a bridging agent), and alizarin red (GO-Al-AR). The fluorescence of the complex (with excitation/emission maxima at 440/512 nm) is weak but significantly enhanced upon the addition of lysine, probably due to a photoinduced electron transfer signalling mechanism. The method has a detection limit of 2 mg L−1 of lysine and a linear range from 25 mg L−1 to 250 mg L−1. It was applied to image lysine in human retinal pigment epithelium cells. |
| Databáze: | OpenAIRE |
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