Carpentier-Edwards Bioprosthesis: Structural Deterioration by Age Groups

Autor: WR Eric Jamieson, Guy Fradet, Robert T Miyagishima, A Ian Munro, Samuel V Lichtenstein, L. H. Burr, Hilton Ling
Rok vydání: 1997
Předmět:
Zdroj: Asian Cardiovascular and Thoracic Annals. 5:193-198
ISSN: 1816-5370
0218-4923
DOI: 10.1177/021849239700500402
Popis: The Carpentier-Edwards supra-annular porcine bioprosthesis (second generation prosthesis) was implanted in 2438 patients in 2482 operations between 1982 and 1992. The mean age of the population was 64 years with a range from 21 years to 89 years. There were 1334 aortic and 934 mitral valve replacements. The population was divided into five groups: 21 to 40 years (n = 132); 41 to 50 years (n = 189); 51 to 60 years (n = 454); 61 to 70 years (n = 849); and over 70 years (n = 858). There was no difference in sunival by valve position for age groups 21 to 40 years and 41 to 50 years. Sunival within the age groups 51 to 60 years, 61 to 70 years, and over 70 years was greater for patients with aortic compared with mitral and multiple valve replacements. The freedom from structural valve deterioration at 10 years for all age groups was highest for valves in the aortic position. Patients with valves in the mitral position had a higher freedom from structural valve deterioration at 10 years than those who had multiple valve replacement, although not all the differences were significant. There was a lower incidence of structural valve deterioration in the older age groups. We concluded that the use of the Carpentier-Edwards supra-annular porcine bioprosthesis for aortic valve replacement can be extended to patients over 60 years of age, while its use for mitral valve replacement can be extended to those above 70 years of age.
Databáze: OpenAIRE