A Rare Case of Holoprosencephalus with Cyclopia
| Autor: | Aliou Diouf, Ousmane Thiam, Cheikh C. T. Sarr, Mame Diarra Ndiaye, Magatte Mbaye, D. Sow, Mamour Gueye |
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| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Open Journal of Obstetrics and Gynecology. 10:976-980 |
| ISSN: | 2160-8806 2160-8792 |
| DOI: | 10.4236/ojog.2020.1080092 |
| Popis: | Cyclopia is a rare genetic defect. It is the most severe form of alobar holoprosencephaly, characterized by the fusion of the two orbits and is linked to the lack of development of the frontal bud falling within the framework of ectroprosopia. Case presentation: This is a case report of Gravida 3 Para 3, 32 years old and without a history of abortion, with a history of normal vaginal birth which occurs during labor latency with active movements of the fetus present and cardiac activity on auscultation with pinard stethoscope. The uterine height was 32 cm with well palpated fetal poles. Ultrasound examination confirms the presence of normal cardiac activity with a poorly responsive fetus. After labor management, she gave birth 3 hours after admission to the maternity ward of a living newborn male weighing 2800 g with an Apgar score of 4/10 at the first minute and 2/10 at the fifth minute. He died 10 minutes later at the maternity hospital of the Saint-Louis regional hospital center, in northern Senegal. Conclusion: Holoprosencephaly is certainly rare but remains the most common structural congenital anomaly of the brain with a complex and multifactorial pathogenesis. Early perinatal diagnosis and determination of severity are important to inform parents of the possibilities of a future life. The voluntary termination of pregnancy is an option but remains prohibited in the country to this day for these indications. |
| Databáze: | OpenAIRE |
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