A comparison of the acute toxicities using moderate hypo-fractionated intensity-modulated radiation therapy or volumetric modulated arc therapy for the treatment of early-stage prostate cancer
| Autor: | Helen Warren-Forward, Shane E. Dempsey, Craig A. Elith |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Oncology
medicine.medical_specialty Urinary retention business.industry medicine.medical_treatment Urinary system Urology Common Terminology Criteria for Adverse Events Urinary Tract Pain medicine.disease Radiation therapy Prostate cancer medicine.anatomical_structure Prostate Internal medicine medicine Radiology Nuclear Medicine and imaging medicine.symptom business Proctitis |
| Zdroj: | Journal of Radiotherapy in Practice. :1-11 |
| ISSN: | 1467-1131 1460-3969 |
| DOI: | 10.1017/s1460396915000242 |
| Popis: | AimThis study compared the acute toxicities reported during radiotherapy treatment using either intensity-modulated radiation therapy (IMRT) or volumetric-modulated arc therapy (VMAT) to deliver a moderate hypo-fractionated treatment for early-stage prostate cancer.Material and methodsAcute toxicities are routinely reported at the clinical site for all patients using the Common Terminology Criteria for Adverse Events. Toxicity assessment is performed on day 1 of treatment, then once weekly thereafter. The recorded toxicities of 40 cases treated with five-field IMRT, and 32 cases treated using VMAT were retrospectively compared. All cases were prescribed 73·68 Gy in 28 fractions. Eight symptoms were assessed; diarrhoea, proctitis, fatigue, pain, dermatitis, urinary frequency, urinary retention and urinary tract pain.ResultsIn terms of the overall toxicity recorded, VMAT was shown to reduce the toxicities of dermatitis, fatigue, pain and urinary frequency (pFindingsThe research reported here is one of the first publications to demonstrate that VMAT is associated with decreased toxicities compared with IMRT for the treatment of early-stage prostate cancer. |
| Databáze: | OpenAIRE |
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