Fabrication of Fe3 O4 /PLLA composites for use in bone tissue engineering
| Autor: | Wei Jen Chang, Haw Ming Huang, Hsin Ta Wang, Kang Hsin Fan, Yu Hwa Pan, Ting Lin Wu |
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| Rok vydání: | 2016 |
| Předmět: |
Materials science
Fabrication Polymers and Plastics Scanning electron microscope Composite number 02 engineering and technology General Chemistry Molding (process) 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Tissue engineering Ultimate tensile strength Materials Chemistry Ceramics and Composites Composite material 0210 nano-technology Nanoscopic scale Elastic modulus |
| Zdroj: | Polymer Composites. 38:2881-2888 |
| ISSN: | 0272-8397 |
| Popis: | The aim of this study was to incorporate nanoscale Fe3O4 particles into a poly-L-lactide (PLLA) matrix to fabricate a magnetic and biodegradable composite. The physical and osteogenic functions of this material were tested. Injection molding was used to fabricate four nano-Fe3O4/PLLA composites with Fe3O4 mix ratios of 0%, 20%, 30%, and 40% (w/w). X-ray diffraction and hysteresis loop tests were performed to evaluate the physical properties of the nano-Fe3O4/PLLA composites. Tensile strength tests showed that the progressive addition of nano-Fe3O4 particles to the PLLA matrix results in higher elastic modulus and lower tensile strength. Images from scanning electron microscopy demonstrated that osteoblasts cultured on the 20% nano-Fe3O4/PLLA surface exhibited abundant filaments, which are a morphologic characteristic of osteoblastic differentiation. These results suggest that the 20% nano-Fe3O4/PLLA composite used in this study has the potential for future tissue engineering applications. POLYM. COMPOS., 2016. © 2016 Society of Plastics Engineers |
| Databáze: | OpenAIRE |
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