Antioxidant Property of Triphala on Cold Stress Induced Oxidative Stress in Experimental Rats
| Autor: | R Srikumar, Selvakumar Dhanalakshmi, Sundaramahalingam Manikandan, Narayanaperumal Jeya Parthasarathy, Rathinasamy Sheela Devi |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
chemistry.chemical_classification
Antioxidant Vitamin C biology Chemistry Health Toxicology and Mutagenesis medicine.medical_treatment Glutathione peroxidase Pharmacology Toxicology medicine.disease_cause Terminalia chebula Lipid peroxidation Superoxide dismutase chemistry.chemical_compound Biochemistry medicine biology.protein Triphala Oxidative stress |
| Zdroj: | Journal of Health Science. 52:843-847 |
| ISSN: | 1347-5207 1344-9702 |
| DOI: | 10.1248/jhs.52.843 |
| Popis: | number of diseases. The present study was aimed to investigate the antioxidant properties of Triphala (Terminalia chebula, Terminalia bellerica and Emblica officinalis) during cold-stress. Four groups of albino rats were employed namely control, Triphala, coldstress and Triphala with cold-stress. The oxidative stress was assessed by measuring the lipid peroxidation (LPO), enzymatic superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and non-enzymatic (Vitamin C) antioxidant status in adrenal tissue and plasma corticosterone level. Following coldexposure (8° ° ° °C for 16 hr/d/15 days), enzymatic and nonenzymatic antioxidants were significantly reduced with concomitant increase in LPO and corticosterone levels were observed. Administration of Triphala (1 g/kg/ body weight/48 days) significantly prevents the coldstress-induced oxidative stress and elevation in LPO and corticosterone levels. This study concludes that Triphala supplementation significantly prevents the cold-stress-induced oxidative stress may due to its antioxidant properties. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|