ChemInform Abstract: Lithiated Azafulvenes by Halogen/Metal Interchange of Brominated 6-(Diisopropylamino)-1-azafulvene Derivatives. Novel Synthesis of 5-Mono- and 4,5-Disubstituted 1H-Pyrrole-2-carbaldehydes

Autor:	Petr Hess, Joseph M. Muchowski, Markus E. Scheller, Brian L. Bray
Rok vydání:	1989
Předmět:	Metal chemistry.chemical_compound chemistry visual_art Reagent Halogen Polymer chemistry visual_art.visual_art_medium Basic hydrolysis General Medicine Pyrrole
Zdroj:	ChemInform. 20
ISSN:	0931-7597
DOI:	10.1002/chin.198911152
Popis:	The first known lithiated 1-azafulvene derivatives were generated by low-temperature halogen/metal interchange, with t-BuLi, from the corresponding brominated 6-diisopropylamino compounds 3b and 12. These Li species reacted with sundry eletrophilic reagents to give products which, on basic hydrolysis, were converted into 5-mono- or 4,5-disubstituted pyrrole-2-carbaldehydes 10 and 16, respectively.
Databáze:	OpenAIRE
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