Noninvasive depth-resolved optical measurements of the tympanic membrane and middle ear for differentiating otitis media

Autor:	Guillermo L. Monroy, Ryan M. Nolan, Malcolm C. Hill, Daniel T. McCormick, Ryan L. Shelton, Stephen A. Boppart, Cac T. Nguyen, Michael A. Novak
Rok vydání:	2015
Předmět:	medicine.medical_specialty Diagnostic information Pathology medicine.diagnostic_test business.industry Optical measurements Normal group Otitis medicine.anatomical_structure Otorhinolaryngology Optical coherence tomography Ophthalmology medicine Middle ear medicine.symptom business Normal thickness
Zdroj:	The Laryngoscope. 125:E276-E282
ISSN:	0023-852X
DOI:	10.1002/lary.25141
Popis:	Objective/Hypothesis In this study, optical coherence tomography (OCT) is used to noninvasively and quantitatively determine tympanic membrane (TM) thickness and the presence and thickness of any middle-ear biofilm located behind the TM. These new metrics offer the potential to differentiate normal, acute, and chronic otitis media (OM) infections in pediatric subjects. Study Design Case series with comparison group. Methods The TM thickness of 34 pediatric subjects was acquired using a custom-built, handheld OCT system following a traditional otoscopic ear exam. Results Overall thickness (TM and any associated biofilm) was shown to be statistically different for normal, acute, and chronic infection groups (normal-acute and normal-chronic: P value
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8401bcea22332f7edfc4b2fe0cac51c5 https://doi.org/10.1002/lary.25141 Zobrazit plný text záznamu Plný text