Re-Neurolysis and Infiltration of Autologous Lipoaspirate Around the Median Nerve in Secondary Recurrent Carpal Tunnel Syndrome: A Prospective Cohort Study

Autor: Sjoerd B. Paulusma, Joris A van Dongen, Michiel A. Tellier, Geraldine L. Nanninga, Olivier F E Gostelie, J. Henk Coert, Jean Jaquet
Rok vydání: 2020
Předmět:
Zdroj: SSRN Electronic Journal.
ISSN: 1556-5068
DOI: 10.2139/ssrn.3522582
Popis: Background: Release of the flexor retinaculum in carpal tunnel syndrome (CTS) is a frequently executed operation. Recurrent CTS is mostly caused by new fibrous perineural adhesions around the median nerve. Extensive neurolysis is advised in a first recurrent episode. In case of secondary recurrence, addition of an interposition of vascularised fat- fascia or muscle- tissue after an extensive neurolysis is suggested. Most of these techniques are labour-intensive and cause donor site morbidity. The authors hypothesised that lipografting following extensive neurolysis reduces postoperative recurrence of CTS. Methods: In this prospective cohort study, patients with a 2nd to 5th recurrent CTS (N=25) are included and treated with extensive external neurolysis followed by perineural lipografting. Primary outcome is the Boston Carpal Tunnel Questionnaire (BCTQ). Secondary outcome is electrodiagnostic nerve conduction velocity obtained with electromyography (EMG). Data are obtained pre-and post-operatively with a mean follow-up of 30 months. Findings: A significant decrease of 1.3 of the total BCTQ scores was seen postoperative (p
Databáze: OpenAIRE