Dithieno-1,4-thiazines. Part I
| Autor: | Cor J. Grol, J. S. Faber |
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| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Recueil des Travaux Chimiques des Pays-Bas. 89:68-73 |
| ISSN: | 0165-0513 |
| DOI: | 10.1002/recl.19700890110 |
| Popis: | The synthesis of the first dithieno[2,3-b : 2′,3′-e]-1,4-thiazine is described, this compound was prepared by condensation of 3-thiophenethiol with methyl 2-bromo-3-nitrothiophene-5-carboxylate followed by reduction, acylation, bromination with NBS and ringclosure with Cu, K2CO3 in nitrobenzene. A thieno-1,4-benzothiazine was prepared in the same way. These compounds were synthesized in order to study the suggested correlation between charge-transfer complexes vs. physiological activity. |
| Databáze: | OpenAIRE |
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