In vivo fibrinolytic Effect of Various Proteolytic Enzymes: Quantitative Tests Employing Iodine131-Labeled Clots**LaWall Memorial Laboratory of Pharmacology and Biochemistry, Department of Pharmacology, Graduate School, Philadelphia College of Pharmacy and Science, Philadelphia 4, Pa

Autor:	Joseph W.E. Harrisson, N. Back, S. Goldstein, C.M. Ambrus, J L Ambrus
Rok vydání:	1959
Předmět:	chemistry.chemical_classification Enzyme Biochemistry chemistry In vivo medicine Proteolytic enzymes Biology Fibrinogen Fibrinolytic agent circulatory and respiratory physiology medicine.drug
Zdroj:	Journal of the American Pharmaceutical Association (Scientific ed.). 48:298-301
ISSN:	0095-9553
DOI:	10.1002/jps.3030480511
Popis:	Purified fibrinogen was labeled with I 131 . Clots were produced in various blood vessels of dogs with the aid of this material. Radioactivity was continuously registered over the clot. Thus, the clot dissolving activity of potential fibrinolytic agents could be evaluated quantitatively. Four roteolytic enzymes of animal and plant origin were found to be ineffective as fibrinolytic agents.
Databáze:	OpenAIRE
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