A divergent approach to cryptotackieine and cryptosanguinolentine alkaloids

Autor:	Pedro Molina, Pilar M. Fresneda, Santiago Delgado
Rok vydání:	1999
Předmět:	chemistry.chemical_compound Computational chemistry Chemistry Insertion reaction Microwave heating Intramolecular force Organic Chemistry Drug Discovery Trimethylphosphine Organic chemistry Biochemistry Derivative (chemistry)
Zdroj:	Tetrahedron Letters. 40:7275-7278
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(99)01477-x
Popis:	A seven-step synthesis of the 1-methyl-3-( o -azidophenyl)quinolin-2-one, a common intermediate for the synthesis of the cryptotackieine and cryptosanguinolentine alkaloids, is described. This intermediate is directly converted into cryptotackieine 1 by an intramolecular aza-Wittig reaction with trimethylphosphine; alternatively heating followed by reduction of the resulting indoloquinoline derivative provided cryptosanguinolentine 2 .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::83ebfee3ce7fd1debfe21d629d55caff https://doi.org/10.1016/s0040-4039(99)01477-x Zobrazit plný text záznamu Full Text from ScienceDirect