Metal complexes of nitrogen-oxygen donor ligands as potential drugs

Autor:	Said A. Ibrahim, M. A. El-Gahami, S. A. El-Gyar
Rok vydání:	1991
Předmět:	Antifungal Azo compound Denticity medicine.drug_class Chemistry Stereochemistry Oxygen donor chemistry.chemical_element General Chemistry Conductivity Nitrogen Medicinal chemistry Metal chemistry.chemical_compound visual_art medicine visual_art.visual_art_medium Chelation
Zdroj:	Collection of Czechoslovak Chemical Communications. 56:1333-1339
ISSN:	1212-6950 0010-0765
DOI:	10.1135/cccc19911333
Popis:	Twelve new complexes of Cu(II), Ni(II), Co(II) and Cd(II) with 5-phenyl, 5-p-tolyl and 5-aminothioacetimide-azo-8-hydroxyquinoline have been synthesized. The ligands act as bidentate (NO) chelating agents forming the bis-chelate complexes. Analytical, conductivity, spectral and thermal data are consistent with six coordinated structure in the case of Cu(II), Ni(II), Co(II) and four coordinate structure in the case of the analogues Cd(II). It is identified that the metal chelates possess enhanced antibacterial and antifungal activities relative to the free ligands.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::83c998209ec9c4a740eb5bbfd068fdf8 https://doi.org/10.1135/cccc19911333 Zobrazit plný text záznamu