Experimental evaluation of the impact of low doses of the herbicide 2,4-D in drinking water on some indices of lipid and immune status
| Autor: | Voronkova Ip, Larisa A. Chesnokova, I. V. Mikhaylova, D. S. Karmanova |
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| Rok vydání: | 2019 |
| Předmět: |
Immune status
medicine.medical_specialty Chemistry Health Toxicology and Mutagenesis Leptin Low dose Public Health Environmental and Occupational Health Spleen Lipid metabolism General Medicine 030204 cardiovascular system & hematology Body weight Pollution 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Endocrinology Immune system Internal medicine medicine 030211 gastroenterology & hepatology Body mass index |
| Zdroj: | Hygiene and sanitation. 95:450-454 |
| ISSN: | 2412-0650 0016-9900 |
| DOI: | 10.18821/0016-9900-2016-95-5-450-454 |
| Popis: | There were studied features of the manifestation of incoming with potable water nontoxic doses of the herbicide 2,4-D on the body mass index, some indices of lipid metabolism and immune system in different types of diets in the experiment in rats. There was shown a significant gain in body weight of animals, and MDA and leptin level in the serum under the action of a herbicide in conjunction with a high-calorie diet. In all experimental groups there was noted the increased level of total cholesterol, tendency to the increase of LDL cholesterol. Under the action of the herbicide there was noted an increase of IL-6, TNF-a and the numbers of leukocytes and, on the contrary, the reduction of the number of thymocytes and kariocytes in thymus and spleen. |
| Databáze: | OpenAIRE |
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