Could selected gut microorganisms be diagnostic biomarkers for autism spectrum disorders? Study based on a commercial microbiota test

Autor: Jendraszak M, Gałęcka M, Andrusiewicz M, Regdos A, Pazgrat-Patan M, Kotwicka M
Rok vydání: 2021
Předmět:
DOI: 10.21203/rs.3.rs-396991/v1
Popis: The early-life modifications of intestinal microbiota may impact children's subsequent emotional and cognitive development. Stool samples of three groups of children (including probiotics and non-probiotics) were analyzed. In cases where probiotics were not used, Bifidobacterium spp. levels differed between the ASD and ALG. In healthy non-probiotics use children, strong positive correlations were observed in E. coli and Enterococcus spp. and Bacterioides and Klebsiella spp. In the non-probiotic use ASD group, a strongly negative correlation was observed in Lactobacillus spp., and Faecalibacterium prausnitzii and Akkermansia muciniphila levels. The presented results did not show conclusive evidence that changes in the level of selected intestinal microorganisms are symptomatic for children with ASD.
Databáze: OpenAIRE