SIZE AND SURFACE EFFECT OF GOLD NANOPARTICLES (AuNPs) IN NANOGOLD-ASSISTED PCR

Autor: Li Xueling, Jun Hu, Aili Zhang, Lihua Wang, Xiaodong Zhang, Xueyan Cao, Haikuo Li, Chunmei Wang, Jiehuan Huang, Chunhai Fan
Rok vydání: 2008
Předmět:
Zdroj: Surface Review and Letters. 15:757-762
ISSN: 1793-6667
0218-625X
Popis: Recently, gold nanoparticles ( AuNPs ) were reported to increase the specificity and efficiency of the polymerase chain reaction (PCR). In this paper, we tested the enhancement of AuNPs with five different sizes on the specificity of two-round PCR. The results showed that, except 5.02 nm AuNPs , the AuNPs that could achieve the similar enhancement happened to have nearly the same total surface area. The surface effect seems to be the key factor of nanogold-assisted PCR.
Databáze: OpenAIRE