Efecto del estiramiento miocárdico sobre las frecuencias de activación determinadas mediante análisis espectral durante la fibrilación ventricular
| Autor: | José Millet, Luis Mainar, Vicente López Merino, Antonio Cebrián, Alvaro Fernández-Baldor Martínez, Juan Sanchis, Luis Such, Juan C. Porres, Ángel Ferrero, Joaquín Cánoves, Francisco J. Chorro |
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| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Experimental model business.industry Rabbit heart Ventricular dilatation Dominant frequency medicine.disease Surgery Ventricular activation medicine.anatomical_structure Nuclear magnetic resonance Ventricle Ventricular fibrillation medicine Cardiology and Cardiovascular Medicine business Lateral wall |
| Zdroj: | Revista Española de Cardiología. 55:1143-1150 |
| ISSN: | 0300-8932 |
| DOI: | 10.1016/s0300-8932(02)76777-8 |
| Popis: | Introduction and objectives. The aim of this study was to analyze the effects of myocardial stretching on excitation frequencies, as determined by spectral analysis, during ventricular fibrillation. Methods. In 12 isolated rabbit heart preparations, ventricular activation during ventricular fibrillation was recorded with multiple electrodes. Recordings were obtained before, during and after ventricular dilatation produced with an intraventricular balloon. The dominant frequency of the signals obtained with each of the electrodes was determined by spectral analysis. Results. During the control phase, the mean, minimum and maximum dominant frequencies were, respectively, 14.3 ± 1.7, 12.5 ± 1.7, and 16.2 ± 1.4 Hz, and the average difference between the maximum and minimum frequencies was 3.6 ± 2.1 Hz. This difference was over 4 Hz in four cases, and in no case did it exceed 8 Hz. During ventricular stretching, the mean dominant frequency increased significantly (21.1 ± 6.1 Hz; p < 0.0001), as did the minimum values (14 ± 2.6 Hz; p < 0.05) and especially the maximum values (26.6 ± 7.7 Hz; p < 0.0001). The difference between the maximum and minimum frequencies (12.6 ± 6.4 Hz; p < 0.001) was over 4 Hz in all cases except one, and over 8 Hz in 9 cases. The maximum values were distributed heterogeneously during ventricular stretching. Upon suppressing ventricular stretching, the dominant frequency did not differ from controls. Conclusions. Myocardial frequency maps during ventricular fibrillation show limited variations in the dominant frequency of the signals recorded in the lateral wall of the left ventricle. During stretching, the patterns were heterogeneous, due mainly to the marked increase in the maximum dominant frequency. In the experimental model used, the effects of stretching remitted after suppressing ventricular dilatation. |
| Databáze: | OpenAIRE |
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