Spinal excitability changes do not influence the mechanisms of split-hand syndrome in amyotrophic lateral sclerosis
| Autor: | Metin Mercan, Bülent Cengiz, Reha Kuruoğlu |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Dorsum medicine.medical_specialty Physiology 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Muscle nerve Physiology (medical) Internal medicine medicine In patient Amyotrophic lateral sclerosis Split hand syndrome business.industry Significant difference medicine.disease body regions 030104 developmental biology medicine.anatomical_structure Cardiology Silent period Neurology (clinical) business 030217 neurology & neurosurgery Reinnervation |
| Zdroj: | Muscle & Nerve. 58:503-508 |
| ISSN: | 0148-639X |
| DOI: | 10.1002/mus.26123 |
| Popis: | INTRODUCTION We studied spinal excitability and its relation to motor unit action potential (MUAP) changes in the thenar and hypothenar muscles in patients with amyotrophic lateral sclerosis (ALS). METHODS Quantitative MUAP and peak ratio interference analyses were performed, and cutaneous silent period (CutSP) was measured in the abductor digiti minimi (ADM) and first dorsal interosseous (FDI) muscles of patients with ALS and controls. RESULTS Patients with ALS revealed more prominently increased duration (P = 0.002), number of phases (P = 0.02), size index (P = 0.02), and thickness (P = 0.02) in ADM than in FDI. The number of small segments was significantly decreased in ADM (P = 0.036) compared with controls. CutSP latency was prolonged in both ADM and FDI in ALS (P |
| Databáze: | OpenAIRE |
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