Tuning Mechanical Properties of Chondroitin Sulfate-Based Hydrogels Using the Double-Network Strategy

Autor:	Stevin H. Gehrke, Anahita Khanlari, Tiffany C. Suekama
Rok vydání:	2014
Předmět:	chemistry.chemical_classification Materials science Polyacrylamide Polymer engineering.material chemistry.chemical_compound Monomer chemistry Chemical engineering Polymer chemistry Self-healing hydrogels engineering medicine Chondroitin sulfate Biopolymer Swelling medicine.symptom Ethylene glycol
Zdroj:	MRS Proceedings. 1622:79-84
ISSN:	1946-4274 0272-9172
Popis:	The double-network (DN) hydrogel concept developed by J.P. Gong and Y. Osada builds upon interpenetrating networks by combining brittle and ductile components to have significantly enhanced fracture properties. The generality of the DN effect was tested by creating biopolymer-based hydrogels of methacrylated chondroitin sulfate (MCS) and polyacrylamide (PAAm) and extended upon creating DNs of MCS and poly(N,N dimethyl acrylamide) (PDMAAm), verifying that DNs were not limited to the original combination of poly(2-acrylamido-2-methylpropanesulfonic acid) (PAMPS)/polyacrylamide (PAAm). Further, the mechanical properties were varied by changing the monomer concentrations, cross-linker concentrations and the addition of cross-linking groups through copolymerizations of MCS and poly(ethylene glycol) diacrylate (PEGDA). Overall, this work demonstrates that a broad range of mechanical properties achievable through DN effect under tension and compression, generally independent of the swelling degree, which is fundamentally different behavior than possible with single networks.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::838ae99ffa338a2d6342224306d2a2f5 https://doi.org/10.1557/opl.2014.72 Zobrazit plný text záznamu Full text from SpringerLink