Ehrlichia ‐induced hemophagocytic lymphohistiocytosis after autologous stem cell transplant
Autor: | Frits van Rhee, Mary J. Burgess, Angel A Mitma |
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Rok vydání: | 2021 |
Předmět: |
endocrine system
Transplantation Hemophagocytic lymphohistiocytosis biology medicine.drug_class business.industry Ehrlichia Daratumumab Inflammation 030230 surgery Monoclonal antibody medicine.disease biology.organism_classification 03 medical and health sciences 0302 clinical medicine Infectious Diseases hemic and lymphatic diseases Immunology Ehrlichiosis (canine) medicine 030211 gastroenterology & hepatology medicine.symptom Stem cell business Multiple myeloma |
Zdroj: | Transplant Infectious Disease. 23 |
ISSN: | 1399-3062 1398-2273 |
DOI: | 10.1111/tid.13621 |
Popis: | Hemophagocytic lymphohistiocytosis (HLH) causes multiorgan failure due to the release of multiple cytokines mediating widespread inflammation. We present a patient with multiple myeloma on maintenance chemotherapy with the anti-CD38 monoclonal antibody daratumumab after autologous stem cell transplant (ASCT) who developed fatal HLH secondary to Ehrlichiosis. |
Databáze: | OpenAIRE |
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