Structure of an Unusual Tetracyclic Deoxyguanosine Adduct: Implications for Frameshift Mutagenicity of ortho-Cyano Nitroanilines
| Autor: | Richard A. Manderville, Ryan W. Kung, Stacey D. Wetmore, M. Sameer Al-Abdul-Wahid, P. David Josephy, Trevor W. Manning |
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| Rok vydání: | 2019 |
| Předmět: |
endocrine system
0303 health sciences Chemistry Stereochemistry food and beverages General Medicine 010501 environmental sciences Toxicology 01 natural sciences 3. Good health Frameshift mutation Adduct 03 medical and health sciences chemistry.chemical_compound Deoxyguanosine Carcinogen 030304 developmental biology 0105 earth and related environmental sciences |
| Zdroj: | Chemical Research in Toxicology. 33:584-593 |
| ISSN: | 1520-5010 0893-228X |
| Popis: | Nitroaromatic compounds represent a major class of industrial chemicals that are also found in nature. Polycyclic derivatives are regarded as potent mutagens and carcinogens following bioactivation... |
| Databáze: | OpenAIRE |
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