The significance of the level of triiodothyronium in the diagnosis of the syndrome of 'low triiodothyronine' in heart failure

Autor: I.S Rudik, S N Pyvovar, O Medentseva
Rok vydání: 2021
Předmět:
Zdroj: European Heart Journal. 42
ISSN: 1522-9645
0195-668X
Popis: Heart failure (HF) is an important issue in cardiology. Some patients with HF have the low T3 syndrome (LT3S). There is no consensus regarding the criteria for determining LT3S. The purpose is to study the features of LT3S determination in HF and its relationship with the disease course. Materials and methods A total of 157-patients with HF and postinfarction cardiosclerosis were examined. At the I stage, all patients were divided into 2 groups: I – 122 patients with normal level of free T3f, T4f and thyroid-stimulating hormone (TSH); II – 35 patients with LT3S (T3f≤2.5 pmol/l and normal levels of T4f and TSH). At the II stage, 129 patients without LT3S were included into group I and 28 patients with LT3S (T3f ≤2.07 pmol/l) – into group II. Serum levels of TSH, T3f, T4f, reverse T3 (T3r) were determined. Echocardiography was performed. HF course was studied during 2 years. Results The frequency of LT3S (T3f Conclusions The frequency of LT3S (T3f Funding Acknowledgement Type of funding sources: None.
Databáze: OpenAIRE