| Popis: |
Behavioral observations of Drosophila are as old as some of the early genetic studies of this organism. Because the genetics of Drosophila is studied extensively, the appearance of these specific behavioral patterns in adults and larvae has almost immediately led to investigations of their genetic control. Application of Drosophila to the study of movement disorders research must begin with a detailed understanding of fly behavioral genetics. There are obvious complications in all organisms that result in problems for studying the control of behavioral and motor patterns. Drosophila , however, still possess important advantages for these studies. The central nervous system is amenable to study. While it is complex, it is still possible to sort out changes within the brain and the peripheral nervous system. More importantly, however, is the wealth of knowledge associated with the genetic control of behavioral responses in Drosophila . The genetic manipulations resulting in mutagenesis and transgenesis have become standard, and it is probable that deliberate interference with gene activity and intentional interference with physiological processes in Drosophila can lead to a fuller understanding of behavioral and motor functions in higher organisms. |
