Abstract 13291: Impact of VAD Support Duration on Pediatric Heart Transplant Outcomes
| Autor: | Anne I. Dipchand, Arene Butto, Michael P Carboni, Zdenka Reinhardt, Martha Wetzel, Chad Mao, Joshua Sparks, William T. Mahle, Chet R. Villa, Kenneth R. Knecht, Lydia Wright, Michael Kelleman |
|---|---|
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Circulation. 142 |
| ISSN: | 1524-4539 0009-7322 |
| DOI: | 10.1161/circ.142.suppl_3.13291 |
| Popis: | Introduction: There is wide variability in the timing of heart transplant (HT) listing and consideration of organ offers after ventricular assist device (VAD) implant in children. While some centers wait weeks or months before proceeding with HT, others accept donor hearts within days of VAD surgery. We sought to determine if HT within 30 days of VAD implant impacts post-HT outcomes when compared to HT after ≥30 days of VAD support. Methods: Patients on VAD support prior to HT were extracted from the Pediatric Heart Transplant Study database. The primary endpoints were post-HT length of hospital stay (LOS) and one-year survival. Confounding was addressed by propensity score weighting using inverse probability of treatment. Propensity scores were calculated based on age at VAD implant, blood type, primary cardiac diagnosis, decade, VAD type, and allosensitization status. Group balance was verified with standardized differences. Results: A total of 1138 children underwent VAD implant prior to HT between 2000-2019 (Table 1). Most underwent HT ≥30 days after VAD (71%). The majority (70%) had an LVAD alone. Infants accounted for 22% of both groups, while those 1-11 years were 46% of the ≥30-day group and patients ≥12 years made up 42% of Conclusions: In this large study of children undergoing HT after VAD, we found lower one-year survival in patients on VAD support for |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|