Effect of preoperative exercise on vascular caliber and maturation of arteriovenous fistula: the physicalfav trial, a randomized controlled study

Autor: Nicolás Macías, Soledad Manzano Grossi, Silvia Caldés, Yolanda Hernandez Hernandez, Marian Goicoechea, Belen Ramirez Senent, Inés Aragoncillo Sauco, Covadonga Hevia, Yésika Amézquita
Rok vydání: 2021
Předmět:
Zdroj: Journal of Nephrology. 34:763-771
ISSN: 1724-6059
1121-8428
DOI: 10.1007/s40620-020-00907-w
Popis: Autologous arteriovenous fistula (AVF) is the best vascular access for hemodialysis. Distal forearm radiocephalic fistula is the best option, although the primary failure rate ranges from 20% to 50%. The main objective of the PHYSICALFAV trial was to evaluate the effect of preoperative isometric exercise on vascular caliber, percentage of distal arteriovenous fistula, and primary failure rate. The PHYSICALFAV trial (NCT03213756) is an open-label, multicenter, prospective, randomized, controlled trial (RCT). A total of 138 patients were randomized 1:1 to the exercise group (exercises combining a handgrip device and an elastic band for 8 weeks) or the control group (no exercise) and followed up with periodic Doppler ultrasound (DU) examinations. After 8 weeks of preoperative isometric exercise, in the exercise group, significant increases were detected in venous caliber (2.80 ± 0.95 mm vs 3.52 ± 0.93 mm [p
Databáze: OpenAIRE