A Giant Lung Tumor Disappeared After Crizotinib Treatment in an Elder Heavy Smoker: a Case Report

Autor:	Yihan Wang, Zhong Zuo, Yuxi Zhu, Hong-Tao Tie
Rok vydání:	2021
Předmět:	Lung Crizotinib medicine.drug_class business.industry medicine.disease respiratory tract diseases ALK inhibitor medicine.anatomical_structure hemic and lymphatic diseases Rare case Cancer research medicine Adenocarcinoma Lung tumor ALK Rearrangement business Complete response medicine.drug
Zdroj:	SN Comprehensive Clinical Medicine. 3:343-345
ISSN:	2523-8973
Popis:	Updated data referring to efficacy and safety of crizotinib therapy have been presented. We reported a rare case of the 71-year-old elder heavy smoker with ALK-rearranged advanced lung adenocarcinoma. Within 7 months of crizotinib treatment, the giant lung tumor disappeared, and a complete response was achieved. The case illustrates exemplarily that crizotinib is effective and manageable as a first-line treatment in advanced NSCLC with ALK rearrangement. It also implies that the elder heavy smoker with such rare “god-given” ALK rearrangement might benefit more from ALK inhibitor.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::832907e498eb031185b0f87fee33c34f https://doi.org/10.1007/s42399-020-00685-3 Zobrazit plný text záznamu Full text from SpringerLink