Quorum sensing — Polymicrobial challenge in periodontics

Autor:	Jaishree Tukaram Kshirsagar, Padmalochani B, Sangeetha S, Sai Sarath Kumar Kothimbakkam, Burnice Nalina Kumari C
Rok vydání:	2020
Předmět:	Quorum sensing Immune system Molecular level Periodontal disease Cell to cell communication Biofilm bacteria Virulence biochemical phenomena metabolism and nutrition Biology Pathogenicity Microbiology
Zdroj:	IP International Journal of Periodontology and Implantology. 4:115-119
ISSN:	2457-0087 2581-9836
DOI:	10.18231/j.ijpi.2019.025
Popis:	Periodontal disease is a multifactorial disease caused by imbalance between complex microbial community and the host immune response. Plaque provides favorable environment for the survival and growth of microorganisms inducing periodontal disease. The current concept of biofilm formation and cell to cell communication of microorganisms present in the biofilm occurs by the production of chemical signaling molecules which has become the niche for molecular level research projects. This biological process is called quorum sensing which modulates the expression of genes involved in survival, biofilm formation, virulence and pathogenicity of microorganisms. To eradicate this communication, quorum quenchers play a role in the inhibition of signals of quorum sensing. This review article enlightens the quorum sensing signaling and the magical action of quorum quenchers from the data collected by different analysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::82f1cf7d9599cf868501bd4651a40db6 https://doi.org/10.18231/j.ijpi.2019.025 Zobrazit plný text záznamu