Pantoea agglomerans Bloodstream Infection in Preterm Neonates
| Autor: | Prem A. Nagaraja, Nasser Yehia A. Aly, Reda A. Abo Lila, Hadeel N. Salmeen |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
biology business.industry Incidence (epidemiology) Pantoea General Medicine Case presentation bacterial infections and mycoses biology.organism_classification Pantoea agglomerans Internal medicine Bloodstream infection medicine Intensive care medicine business human activities |
| Zdroj: | Medical Principles and Practice. 17:500-503 |
| ISSN: | 1423-0151 1011-7571 |
| Popis: | Objective: To report an uncommon incidence of sporadic bloodstream infection (BSI) caused by Pantoea agglomerans in preterm neonates. Case Presentation and Intervention: Fives cases of nosocomial BSI with P. agglomerans in preterm neonates (weight ≤1,500 g; age 8–17 days; gestational age 26–30 weeks) are presented. All cases were late onset neonatal sepsis (>7 days of age). Lethargy, skin mottling and bradycardia were often present. Although there was no evidence of pneumonia, desaturation was a common feature. Thrombocytopenia developed in 4 patients, metabolic acidosis in 2 and jaundice in 2. No bleeding tendency or disseminating intravascular coagulation was recorded. Organisms cultured from blood were identified by the Vitek-2 system (bioMérieux, France) and the findings confirmed by testing the isolate on the API 20E system. All isolates shared in vitro susceptibility to gentamicin, amikacin, ciprofloxacin, piperacillin/tazobactam and meropenem. One patient was treated with a cefotaxime/amikacin combination, 2 with meropenem and the remaining 2 with tazocin. All patients responded well to antibiotic treatment and survived. Conclusion:P. agglomerans is an unusual pathogen in the etiology of neonatal sepsis. Despite significant clinical deterioration, early detection and proper antibiotic therapy carry a favorable outcome. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|