Antimicrobial Potency of Methanolic Leaf Extracts from Selected Medicinal Plants against Staphylococcus aureus
| Autor: | Rachuonyo Ho, Arika Wm, Kiboi Ng, Wambani, Ogola Pe |
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| Rok vydání: | 2016 |
| Předmět: |
Tagetes minuta
biology Traditional medicine 010405 organic chemistry medicine.drug_class Antibiotics biology.organism_classification medicine.disease_cause Antimicrobial 01 natural sciences food.food 0104 chemical sciences Microbiology 010404 medicinal & biomolecular chemistry food Staphylococcus aureus medicine Potency Vancomycin Bulbine frutescens Medicinal plants medicine.drug |
| Zdroj: | Journal of Medical Microbiology & Diagnosis. |
| ISSN: | 2161-0703 |
| DOI: | 10.4172/2161-0703.1000219 |
| Popis: | The main aim of the study was to test for the antimicrobial potency of Aloe secundiflora, Bulbine frutescens, Tagetes minuta and Vernonia lasiopus against Staphylococcus aureus. All the plants showed a pronounced antimicrobial activity against Staphylococcus aureus with Tagetes minuta being the most active at low concentrations (MIC 8.9 mg/ml; MBC 10.0 mg/ml) whereas Vernonia lasiopus showing less activity (MIC 12.2 mg/ml; MBC 14.2 mg/ml). The efficacy test was carried out using the disc diffusion method. The standard antibiotics used were ciprofloxacin (5 μg/ml) and vancomycin (3 μg/ml) showed significant antimicrobial activity by producing zones of inhibition of 22 mm and 25 mm respectively. Dimethyl sulphoxide and distilled water were used as negative control. The extracts from the plants were also screened for the presence of phytochemicals with the results showing the presence of flavonoids, alkaloids, tannins and saponins in all the extracts. The study suggested that the selected medicinal plants can be used effectively in the treatment of bacterial infection caused by Staphylococcus aureus. |
| Databáze: | OpenAIRE |
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