Simultaneous biochemical reaction and separation in a rotating annular chromatograph

Autor: P. E. Barker, M.R. Sarmidi
Rok vydání: 1993
Předmět:
Zdroj: Chemical Engineering Science. 48:2615-2623
ISSN: 0009-2509
Popis: Simultaneous biochemical reaction and separation has been carried out successfully for the first time in a continuous rotating annular chromatograph (CRAC) by inverting sucrose to glucose and fructose using the enzyme invertase. The chromatograph was packed with 14.5 dm3 Dowex 50W-X4 calcium form ion exchange resin. Results from the initial experiments indicated that complete conversion could be achieved for feed concentrations of up to 50% w/v sucrose and at feed throughputs of up to 15 kg sucrose per m3 resin/h. Numerical simulation for the combined biochemical and separation on a CRAC has also been carried out. The model was solved using a finite difference method and the results indicate a good agreement between the experimental and the predicted elution concentration profile.
Databáze: OpenAIRE